semaglutide and drinking Ozempic (semaglutide) shows huge reductions in high-risk heavy drinking, in first-ever clinical trial Semaglutide and Alcohol Use #Shorts

This is the storm before the calm, or what we like to call the worse before better paradox

It works by mimicking the glucagon-like peptide-1 (GLP-1) hormone that targets areas of the brain involved in regulating appetite and food intake

All participants were T2DM patients being treated with a combination of metformin, sodium-glucose co-transporter-2, or sulfonylurea

Crossing strategies are: (1) bypassing intranasal route, (2) lipid modifications (Dihexa), (3) active transporters (insulin, transferrin), (4) vehicles like nanoparticles or exosomes

4 Lilly is running Phase 3 studies on orforglipron for the treatment of type 2 diabetes and for weight management in adults with obesity or overweight with at least one weight-related medical problem